Dupuytren's Disease


Dupuytren's disease is a hereditary condition causing abnormal thickening of the tissue layer just under the skin of the palm, known as fascia. Nodules (lumps) may occur. Over a period of time, a contracture may develop, which means the fingers are pulled into a bent position and may be unable to straighten. Dupuytren's contracture is not usually painful. Although the exact cause of this condition is not known, it tends to run in families of Northern European decent and most commonly affects men older than 40. Mild cases of Dupuytren's contracture that do not affect hand function may not require any treatment beyond simple observation. More severe cases may benefit from treatment, including surgery to remove the abnormal tissue or a newer injectable medication (Xiaflex) that can break down the abnormal tissue and allow the finger to be manipulated into a straighter position. (See Dupuytren’s Treatment.)

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